I have SLE and I was wondering if I could have semi permanent make up done?

There is no real reason why you cannot have semi-permanent make-up applied. The risk to your health would be if you suffer from skin manifestations associated to your lupus. It may be advisable to have a skin test first to see if you react. I am not sure what is involved in semi-permanent make-up. Some patients with both discoid lupus and SLE may be allergic to dyes and chemicals and should be aware of a possible reaction.