The true incidence of cancer in SLE has remained unclear, as previous studies found conflicting and incomplete results on the association between certain cancers and lupus.
Here researchers conducted systemic review and meta-analysis of 3 online databases, which included 24 eligible studies in which they found elevated overall risk of 16 cancer types among patients with SLE -- both women and men -- with a pooled standardized incidence rate (SIR) of 1.28 (95% CI 1.16-1.42), according to Xiaoyun Xu, MD, and colleagues from Nanjing Medical University in China.
Specifically, researchers found epidemiological evidence that SLE was associated with 16 cancer types in both genders, and a decreased risk for prostate cancer and cutaneous melanoma.
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