Recurrent lupus nephritis less frequent after kidney transplant

Lupus nephritis is recurring less frequently among patients with end-stage renal disease who undergo kidney transplant, possibly due to improved immunosuppression, according to data presented by Debendra N. Pattanaik, MBBS, MD, of the University of Tennessee Health Science Center.

“We have made a lot of progress in treating lupus nephritis in terms of the immunosuppressive regimen,” Pattanaik told attendees at the ACR/ARHP 2018 Annual Meeting. “However, up to 10% to 30% of patients end up in the end stages of the disease in spite of all the treatment. People in end-stage renal disease end up on dialysis and also undergo kidney transplant. Previous studies have shown that up to 50% of people who receive renal transplant end up getting a recurrence of the disease, but many of these were older studies. We have seen less recurrence in our patients in our clinical practice.”

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