Vitamin D deficiency linked to metabolic changes in patients with lupus

Patients with lupus are more likely to have metabolic syndrome and insulin resistance – both factors linked to heart disease – if they have lower vitamin D levels, according to a study.

Researchers believe that boosting vitamin D levels may improve control of these cardiovascular risk factors, as well as improving long-term outcomes for patients with systemic lupus erythematosus (SLE).

Given that photosensitivity is a key feature of SLE, the scientists say that a combination of avoiding the sun, using high-factor sunblock and living in more northerly countries may contribute to lower levels of vitamin D in lupus patients. Patients with more severe disease also had lower vitamin D levels.

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