Smoking was found to be associated with an increased risk of systemic lupus erythematosus (SLE) among black women, while moderate alcohol consumption significantly reduces the chances of developing the disease, a study reports.
Predictors of medication nonadherence in patients with SLE in Sichuan
The aim of this study was to determine the prevalence and predictors of medication nonadherence among patients with systemic lupus erythematosus (SLE) in Sichuan. A cross-sectional investigation was performed. Participants were recruited by consecutive sampling from the Rheumatic Clinic of a university hospital.
Study suggests Virgin Olive Oil May Help Reduce SLE Activity
Virgin olive oil, especially its phenol components, showed anti-inflammatory properties in mice with systemic lupus erythematosus (SLE) and in human immune cells, according to a new Spanish study. The findings suggest future use in SLE treatment.
The research, “Virgin olive oil and its phenol fraction modulate monocyte/macrophage functionality: a potential therapeutic strategy in the treatment of systemic lupus erythematosus,” was published in the British Journal of Nutrition.
Lupus Overlap in Scleroderma Patients Does Not Seem to Affect Survival
Patients with both scleroderma and systemic lupus erythematosus (SLE) are younger at diagnosis, are more often women, and have less skin manifestations, but most importantly, show similar survival rates as those without lupus, according to a study.
The study, “Epidemiology and Survival of Systemic Sclerosis-Systemic Lupus Erythematosus Overlap Syndrome,” was published in The Journal of Rheumatology.
Infection Is Leading Cause of Death in Lupus Patients in China
In China, mortality rates are higher among women with systemic lupus erythematosus(SLE) than men, with infection being the leading cause of death, a study reports.
According to the researchers, risk factors for poorer outcomes include older age at disease onset, infection, autoimmune anemia, low platelet levels, and pulmonary arterial hypertension.
Lupus affects more women than men. Why? New study explores
Lupus affects nine times more women than men. Experts know that lupus erythematosus, SLE, or lupus affects many more women than men, but none of them can explain why. Now that University of Houston biomedical engineer Chandra Mohan has the funding, he has set out to determine why.
Prof. Mohan, Hugh Roy and Lillie Cranz Cullen Endowed Professor of biomedical engineering, has $2 million to solve the mystery.
Study reveals early signs of cardiac impairment in patients with newly diagnosed lupus
Cardiovascular disease is a leading cause of death in patients with lupus, a systemic autoimmune disease. In a new study in Arthritis & Rheumatology—a journal published by Wiley on behalf of the American College of Rheumatology—imaging tests revealed signs of cardiac impairment in patients newly diagnosed with lupus, even before any symptoms of chest discomfort.
Treatment Goal in Lupus: Low Disease Activity
Corticosteroids Affect Lupus Patients’ Emotional Health, Daily Activities, Study Says
Skin’s Immune ‘Alarm’ May Explain Light-Induced Rashes in Lupus Patients
Lilly to progress Olumiant into Phase 3 for lupus
The Lancet has published full results of a Phase II trial showing the benefit of Lilly’s JAK inhibitor Olumiant in the treatment of global systemic lupus erythematosus (SLE).
According to the data, a statistically significant proportion of patients treated with 4mg of Olumiant (baricitinib) achieved resolution of their SLE-related arthritis or rash compared to placebo at week 24, thus meeting the primary endpoint of the trial.
Scientific and Technology Breakthroughs Show Promise for Lupus and Other Immunologic Diseases
The Lupus Research Alliance is pleased and very encouraged to share a promising scientific breakthrough reported in the New York Times with real potential to revolutionize lupus treatment. Just reported in the prestigious journal Nature, scientists in Dr. Alexander Marson's lab at the University of California, San Francisco have developed an innovative way to engineer genes of the body's immune system to treat immunologic diseases like lupus, rheumatoid arthritis, cancer and HIV.
Levels of Specific Antibodies Linked to Clinical Characteristics of Lupus, Study Reports
Levels of certain antibodies are significantly associated with particular clinical characteristics of systemic lupus erythematosus (SLE), and could be used to assess disease activity in patients, a study finds.
The study, “Antibodies to extractable nuclear antigens (ENAS) in systemic lupus erythematosus patients: correlations with clinical manifestations and disease activity,” was published in the journal Reumatismo.
French Lupus Vaccine Ready to Move Into Phase III
Neovacs, a French biotech, obtained positive Phase IIb results showing its lupus vaccine could be effective in treating this severe autoimmune disease.
Its lupus vaccine works by stimulating the patient’s immune system to produce antibodies against a protein called IFNα that regulates the immune system and is involved in the disease.
