Korean researchers unlock genetic clues to lupus

In a major leap forward for autoimmune disease research, South Korean researchers have developed a high-resolution genetic analysis tool that can precisely decode the complex immune-related gene cluster linked to lupus. This discovery not only deepens understanding of how lupus begins but also could lead to customized treatments tailored to individual genetic profiles, they say.

A team led by Professor Bae Sang-cheol of the Department of Rheumatology at Hanyang University Rheumatology Hospital, in collaboration with Professor Kim Kwang-woo of the Department of Biology at Kyung Hee University Medical Center and the Genomics Division of the National Institutes of Health, announced on Tuesday that they have developed a new genetic analysis tool that can precisely analyze the Major Histocompatibility Complex (MHC) immune gene region, and identified key genetic variants involved in the development of lupus.

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Information from The Korean Herald & Korea Biomedical review.