Lupus Trust UK

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Cells that Fight Viruses May Trigger Immune Responses that Make Lupus Worse

A type of immune cell that protects against viruses and cancer may worsen systemic lupus erythematosus (SLE) and trigger disease flares, a recent study with mice suggests.

Led by researchers at the U.K.’s Imperial College London, the study, “C1q restrains autoimmunity and viral infection by regulating CD8+ T cell metabolism,” appeared in the journal Science.

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